ABSTRACT

Degenerative changes are encountered relatively frequently in uterine leiomyomas. The nature of the change varies according
to the degree and rapidity of onset of vascular insufficiency and is found in one or several of a group of fibroids. In some
instances degeneration is associated with acute and severe symptoms. All these features maybe encountered in malignant tumours and therefore thorough sampling of lesions with unusual gross appearance is imperative. Further, in the presence of extensive degeneration, it is difficult to identify the smooth muscle nature of the lesion. The present study is proposed to be
undertaken, because the gross and microscopic appearances of degeneration may simulate malignant tumors, the diagnosis of these tumors carry better prognosis requires detailed morphological study.