Seroprevalence of hepatitis B virus, hepatitis C virus, HIV, and syphilis among blood donors at a tertiary care teaching hospital in Salem, Tamil Nadu

ABSTRACT

Background: Blood transfusion is a rare, uncommon but important mode of transmission of infections to recipients. This study was conducted to evaluate the markers of human immunodefi ciency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV), and syphilis among blood donors in Salem, Tamil Nadu.
Materials and Methods: A 1-year retrospective study was conducted from June 2013 to June 2014 at the Immunohematology and blood transfusion center at Vinayaka Missions Kirupananda Variyar Medical College, Salem. A total of 3680 donors were tested.
Results: About 59% were replacement donors and 41% were voluntary donors. The seroprevalence of HIV, HBV, HCV, and syphilis was found to be 0.065%, 0.662%, 0.779%, and 0.150% in voluntary blood donors as against the figures 1.063%, 1.382%, 0.323%, and 0.564% in replacement blood donors.
Conclusion: The seroprevalence of HIV, HBV, and syphilis was more in replacement donors than voluntary donors. This calls for mandatory routine screening with more sensitive and stringent screening methods for blood donations.

Prevalence of ABO and rhesus (D) antigens with possible transfusion transmitted infections in correlation to rhesus and ABO blood group systems

ABSTRACT

Objective: The objective was to study the frequency of ABO and Rh (D) blood groups and its correlation to transfusion transmitted infections (TTI) among the blood donors who donated at Vinayaka Mission’s Kirupananda Variyar blood bank, Salem, Tamilnadu.
Materials and Methods: Details about blood grouping and TTI positivity of a total of 17678 potential blood donors were collected from the records of transfusion medicine department of our institution for 3 years period between July 2011 and June 2014. Results: Blood group ‘B’ had the highest incidence and 93.33% of the blood groups tested were Rh positive. ‘A’ blood group with Rh positivity was more commonly associated with TTI.
Conclusion: The most common blood group tested in our blood bank was ‘B positive,’ whereas TTI was common in the ‘A positive’ blood donors.