DENGUE: SEROPREVALENCE, COMPARISON OF RAPID TEST WITH ELISA

ABSTRACT

Introduction: – Dengue is a major health problem in many parts of the tropical world. It is a mosquito borne illness caused by one of the serotypes of dengue viruses.
Aims and objectives: – The present study was done to
know the common clinical features and Seroprevalence of dengue in our region. An attempt was made to compare rapid test SD dengue duo (IgM, IgG & NS-1 Ag detection) with capture ELISA (IgM, IgG Microlisa
Dengue).

Materials & Methods: – 226 serum samples were tested in patients clinically suspected Dengue. All the 226 samples were subjected to IgG, IgM Microlisa test. The same were put on rapid SD bioline Dengue duo rapid test and was compared with ELISA.
Results:- 226 serum samples were tested in patients clinically suspected Dengue before noting common clinical signs and symptoms. 150 samples were tested positive with ELISA (either positive for IgG, IgM or both). Seroprevalence of 66% were reported. When compared with ELISA, Rapid test showed sensitivity of 80.6% specificity and positive predictive value of 100% & zero false positive rates. Efficiency of the test was 87.16%
Conclusion:- High prevalence rate in our region particularly in premonsoon & monsoon season gives an alarm to the doctors regarding early and accurate diagnosis of dengue virus infection. SD Dengue duo rapid test should be a valuable screening test for dengue fever
which can be interpreted easily. Results were comparable to ELISA. It provides additional diagnostic investigation that compliments NS-1 antigen detection.

A study of prevalence of hepatitis c virus in amalapuram, andhra pradesh

ABSTRACT

The prevalence of hepatitis C in patients with liver disease is known to be high and several studies have been carried out to evaluate the burden of this disease in society. However, limited data is available as to the prevalence of HCV in general population, particularly in rural areas of India. To assess the prevalence of HCV infection and risk factors involved among the out patients and in patients of Orthopaedics, Gynaecology and Surgery departments of Konaseema Institute of Medical sciences, Amalapuram, India.