Background: Blood transfusion is a rare, uncommon but important mode of transmission of infections to recipients. This study was conducted to evaluate the markers of human immunodefi ciency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV), and syphilis among blood donors in Salem, Tamil Nadu.
Materials and Methods: A 1-year retrospective study was conducted from June 2013 to June 2014 at the Immunohematology and blood transfusion center at Vinayaka Missions Kirupananda Variyar Medical College, Salem. A total of 3680 donors were tested.
Results: About 59% were replacement donors and 41% were voluntary donors. The seroprevalence of HIV, HBV, HCV, and syphilis was found to be 0.065%, 0.662%, 0.779%, and 0.150% in voluntary blood donors as against the figures 1.063%, 1.382%, 0.323%, and 0.564% in replacement blood donors.
Conclusion: The seroprevalence of HIV, HBV, and syphilis was more in replacement donors than voluntary donors. This calls for mandatory routine screening with more sensitive and stringent screening methods for blood donations.